| abstract |
A family of chlorins, a family of purpurins and metal complexes thereof are disclosed. The purpurins have the formula of Fig. 5 of the attached drawings; their metal complexes have the formula of Fig. 1. The chlorins have the formula of Fig. 6 of the attached drawings; their metal complexes have the formula of Fig. 2. Solutions of the purpurins, chlorins and metal complexes which are physiologically acceptable for intravenous administration are also disclosed, as are emulsions or suspensions of the solutions. The solvent for the solutions can be a product of the reaction of ethylene oxide with castor oil. A method for detecting and treating tumors in human and animal patients is also disclosed. The method comprises administering one of the purpurins, chlorins or metal complexes to the patient. For detection, the tumor area is then illuminated with ultra violet light; for treatment, the tumor area is illuminated with visible light of a wavelength at which the purpurin, chlorin or complex administered shows an absorption peak. |