http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8702662-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bba842fc4d37dfcaced1b55bc0c91c7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_421a5ad8d7d7f185b00d3545dbe2e0f6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-24 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-337 |
| filingDate | 1986-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87591e894e3e0058673663df8c3abfc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55d3d88e157d58ef9dd7b32140b1c34e |
| publicationDate | 1987-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-8702662-A2 |
| titleOfInvention | Heterocyclic analogs of mevalonolactone and derivatives thereof, processes for their production and their use as pharmaceuticals |
| abstract | Compounds of formula (I), wherein Ra is a group -X-Z, Rb is R2, Rc is R3, Rd is R4 and Y is a group (III), or Ra is R1, Rb is a group -X-Z, Rc is R2, Rd is R3 and Y is O, S or a group (IV); R1, R2, R3 and R4 independently are C1-6alkyl not containing an asymmetric carbon atom, C3-7cycloalkyl or a ring formula (V), or in the case of R3 and R4 additionally hydrogen, or for R3 when Y is O or S formula (VI), whereby R17 is hydrogen or C1-3alkyl and R18 and R19 are independently hydrogen, C1-3alkyl or phenyl; each R5 is independently hydrogen, C1-3alkyl, n-butyl, i-butyl, t-butyl, C1-3alkoxy, n-butoxy, i-butoxy, trifluoromethyl, fluoro, chloro, bromo, phenyl, phenoxy or benzyloxy; each R6 is independently hydrogen, C1-3alkyl, C1-3alkoxy, trifluoromethyl, fluoro, chloro, bromo, phenoxy or benzyloxy, and each R7 is independently hydrogen, C1-2alkyl, C1-2alkoxy, fluoro or chloro, with the proviso that there may only be one each of trifluoromethyl, phenoxy or benzyloxy in each ring A present, X is (CH2)m or (CH2)qCH=CH-(CH2)q, m is 0, 1, 2 or 3 and both q's are 0 or one is 0 and the other is 1, formula (II), wherein R9 is hydrogen or C1-3alkyl, in free acid form, or in the form of an ester or delta-lactone thereof or in salt form as appropriate, which compounds are indicated for use as pharmaceuticals in particular as hypolipoproteinemic and anti-atherosclerotic agents. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4822799-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5128366-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5919464-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5958966-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0464845-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6369084-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6369082-B1 |
| priorityDate | 1985-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 350.