abstract |
Process for the production of acids of formula (IV) where R is 2-fluoro-4-(1,1'-biphenyl), 4-(2-methylpropyl)phenyl, 6-methoxy-2-napthyl, 3-benzoylphenyl, 4-(2-thienylcarbonyl)-phenyl or 7-chlorocarbazole-3-yl which comprises contacting an organometallic compound of the formula R-M-R1 (G) with an allyl halide of formula (V) to produce an olefin of formula (II) ozonolysis of the olefin (II) to produce an aldehyde of formula (III) which is oxidized either directly to the acid (IV) or via a bisulfite adduct of formula (VI). |