| abstract |
Various embodiments of an improved reconstitution device (30), (168), (170), (186), (242), (256) and (274), directed to the proper mixing of two substances, and are particularly directed to the medical field for the reconstitution of a drug (36) which may be stored in a drug vial (32) with a diluent (60) stored in a flexible medical solution container (34) and used for the intravenous delivery of a medicament. In one embodiment the reconstitution device (30) includes an improved vial adapter (76) and bag adapter (78) which permit the permanent coupling of the vial (32) and liquid container (34). The bag adapter (78) may be rotatable relative to the vial adapter (76) to operate a valve including a stem channel (108) and a base post (148) on the vial adapter (76), a base segment channel (136) and a cut portion (146) of a rim (140) on the bag adapter (78), and a sealing segment (80) disposed between the vial and bag adapter (76) and (78). The reconstitution device (30) reduces drug waste in hospitals, eliminates the need to relable flexible parenteral solution containers after a drug has been added, and prevents repeated exposure of hospital personnel to various drugs. |