http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8600522-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56ee5285e8e8edccb061046ff20da7a6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-15 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-15 |
filingDate | 1985-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85f6a3cb8f4df7dc28c962bcd2b2963a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad5cf2c16fde505b8ba2982a0a418207 |
publicationDate | 1986-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-8600522-A1 |
titleOfInvention | UTILIZATION OF alpha-CETOCARBONIC ACID HYDRAZONES AND OXINES FOR TREATING CARDIAC OR CIRCULATORY DISEASES |
abstract | New medical utilization of alpha -cetocarbonic acid hydrazones and oxines having the general formula (I) wherein I represents an oxygen atom or a group-NH-; Z is a saturated or unsaturated straight or branched chain alkyl group having up to 8 atoms of carbon, optionally substituted once or a plurality of times by a halogen or a hydroxy; R1 is hydrogen, nitrile, formyl or an alkyl group comprising from 1 to 8 C optionally substituted once or a plurality of times by halogen, hydroxy, nitrile, phenyl or carboxyl; R2 represents a saturated or unsaturated straight or branched chain alkyl group with up to 14 atoms of carbon; an alkoxy group comprising from 1 to 6 C or alkylthio having from 1 to 6 C substituted optionally by a lower alkoxy, a cycloalkyl or an aryl; a cycloalkyl group comprising from 3 to 8 C; a phenyl amino; phenyl-N-alkylamino; phenylmercapto; aryl; or aryloxy; these last five substituents being optionally substituted in the aryl part once or a plurality of times by an alkyl comprising from 1 to 6 C, an alkoxy having from 1 to 6 C, a halogen, trifluoromethyl, hydroxy, amino, acetylamino, acetoxy, cyano, nitro or the methylendioxy group; as well as the salts, esters and amides thereof which are physiologically acceptable for the prophylaxis and/or treatment of cardiac and circulatory diseases, particularly ischemic cardiac diseases such as cardiac insufficiency, angina pectoris or myocardial infarction. |
priorityDate | 1984-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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