abstract |
Electrolyte solutions which are useful in electrolyte and fluid therapy, parenteral nutrition, and dialysis. The Na:Cl ratio is normalized, plasma and cellular pH are normalized, and cellular co-factor ratios are normalized, in a manner which decreases toxicity over prior art solutions. The solutions employ at least one of the following near-equilibrium couples: (a) bicarbonate/CO2; (b) 1-lactate/pyruvate; and (c) d-betahydroxybutyrate/acetoacetate. |