Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b21f650fc35b3e1947103e89adb06f3f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-16622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-849 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10322 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-22022 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 |
filingDate |
1984-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42cf319b49cfd901485227ed1f122dd4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34a92ec569a785db4a630a7f7493f046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_147e108f3e348419dbf90b3ef14b2024 |
publicationDate |
1984-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-8404540-A1 |
titleOfInvention |
Hybrid viral plasmid and microorganisms containing same |
abstract |
pML BK is a hybrid plasmid which is constructed of pML which contains the entire nucleotide sequence of the plasmid pBR322 except for deletion of nucleotide sequences 1120-2490 bp and 0 to 375 bp, and BK which contains the entire nucleotide sequence of the Gardner strain of BK virus except for deletion of nucleotide sequences between bp 5089-5196. Into the pML BK plasmid may be inserted a viral or human gene X to be expressed, an example of which is TK which represents the Bam HI generated 3,600 bp DNA fragment of herpes simplex virus type 1 which contains the herpes simplex virus type 1 TK DNA. The majority of the pML BK X DNA molecules remain in the episomal or free state in the human cells 143B and express the gene X. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9302202-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0263328-A1 |
priorityDate |
1983-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |