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filingDate 1984-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_963e4d2add708e0bd7d21e92837d7181
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publicationDate 1984-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-8403700-A1
titleOfInvention 1,4-benzothiazin-3-one derivatives
abstract 1,4-Benzothiazin-3-one derivatives represented by general formula (I), wherein x1 represents hydrogen, halogen, lower alkyl, lower alkoxy, trifluoromethyl, sulfamoyl, N-(lower alkyl)sulfamoyl, N,N-di(lower alkyl)-sulfamoyl, or morpholinosulfonyl, X2 represents halogen, lower alkyl, lower alkoxy, trifluoromethyl, sulfamoyl, N-(lower alkyl)sulfamoyl, N,N-di(lower alkyl)sulfamoyl or morpholinosulfonyl, R represents hydrogen or lower alkyl, R1 and R2 each represents hydrogen or lower alkyl or, together with the adjacent nitrogen atom, R1 and R2 form a heterocyclic ring optionally containing N-R3 (R3: lower alkyl) or oxygen, or pharmaceutically acceptable acid addition salts thereof, and medicinal compositions containing same. The compounds have hypotensive and diuretic effects, and are useful as agents for treating hypertension and chromic edema.
priorityDate 1983-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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