| abstract |
Trisubstituted guanidins bound to a piperidin cycle. The invention relates to carboxamidoguanidins having the general formula (I) wherein R1, R2, R3 and R4 are substituents, n is 0 or 1, n' is 0 or 1, A and B are CH2, CHOH, CO or a single bond. The compounds have the general formula (I) as well as the additional salts thereof have useful hypotensive properties which make them appropriate as active principles in pharmaceutical compositions. |