| abstract |
New s-triazole AD1,5-α BDpyrimidine derivatives represented by the general formula (I): $ (7,) $ in which R1 and R2 may be the same or different, each representing a linear or branched alkyl group with from 1 to 6 carbon atoms, a phenyl group or a hydrogen atom, R3 represents a linear or branched alkyl group containing from 1 to 6 carbon atoms or a hydrogen atom, R4 represents a linear or branched alkyl group containing from 1 to 6 carbon atoms, a phenyl group or a substituted phenyl group, and R5 represents a hydrogen atom or R5 and R1 together form a group - (CH2) -. These compounds have vasodilatory, hypotensive and inhibitory effects on the agglutination of blood platelets, and are useful in the treatment of diseases of the circulatory system. |