http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8000750-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03721e344a72026d125291e6c56c1be6 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-826 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-819 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-804 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-948 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-60 |
filingDate | 1979-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed07169b32f77402cbac19ccfd19bd04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5c0841ee30de68c8271e4bcef09dd65 |
publicationDate | 1980-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-8000750-A1 |
titleOfInvention | Radio receptor assay for benzodizapines in plasma and other biological specimens |
abstract | A rapid, sensitive and specific radioreceptor assay for measuring benzodiazepines in plasma and other biological specimens without sophisticated equipement or methodology. This method is based on the competition between [<s3>sH] diazepam or tritiated flunitrazepam and pharmacologically active benzodiazepines present in plasma, for binding sites on rat brain synaptosomal membranes. No interference is obtained with drag-free plasma or plasma samples containing high concentrations of other commonly used drugs. High correlations (r = 0.98;p < 001) were obtained between the "diazepam equivalents" measured in plasma using the radioreceptor assay and the levels of diazepam and N-demethyl diazepam obtained by gas-liquid chromatography. The radioreceptor assay is useful in monitoring blood benzodiazepine levels for both therapeutic and toxicologic purposes. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2518754-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6465259-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9819166-A1 |
priorityDate | 1978-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.