abstract |
New compounds having the following formula I, (FORMULA) wherein R1 is hydrogen or methyl R3 is hydrogen, methyl, hydroxymethyl, carboxyl, alcoxycarbonyl having 2 to 5 carbon atoms, carbamoyl or cyano and R2 is one of the groups a) to i); these groups are: (FORMULA) and may be used as medicines. These compounds have antiarrhytmic (Alpha)-adrenergic blocking and antihypertension properties; and in case of compounds carrying in position 2 of the indole cycle a cyano or carbamoyl group, (Beta)-adrenergic blocking properties. These compounds are obtained by amination. |