| abstract |
The present invention relates to mono or bi-specific antibodies, or antibody fragments or fusion proteins thereof, capable of binding to the VHL ligand degrading moiety (degron) of a proteolysis targeting chimera (PROTAC) and, optionally, to a target protein. The invention also relates to complexes (PAX) of such antibodies, or antibody fragments or fusion proteins thereof, and PROTACS, as well as methods for their production, and medical as well as non- medical uses each thereof. |