| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966bf992e71058cd39a5aeadebc037df |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-90 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0663
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0667 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 |
| filingDate |
2022-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0077d521e1f201fa7924bf2823a0b65f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d10b1282002dbf1f6ab6dc69ac0c2d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b9219665a9b734b4519e22dba9d548c |
| publicationDate |
2023-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2023274378-A1 |
| titleOfInvention |
Mesenchymal stem cells pretreated by tongxinluo, and preparation method therefor and application thereof |
| abstract |
Provided is a method for improving efficacy of mesenchymal stem cells in the treatment of acute myocardial infarction. The method comprises: using the drug Tongxinluo to pretreat mesenchymal stem cells, wherein improving efficacy of mesenchymal stem cells in the treatment of acute myocardial infarction comprises increasing the expression of chemokine receptor CXCR4. By pretreating mesenchymal stem cells using Tongxinluo, cells having enhanced anti-apoptotic ability and enhanced directional migration ability and mesenchymal stem cells that can improve the microenvironment after myocardial infarction, reduce the infarction area, and improve cardiac function can be prepared. |
| priorityDate |
2021-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |