abstract |
Provided herein are methods for treating a virus (e.g,. an RNA virus, such as a SARS-CoV-2) infection or a disease associated therewith (e.g., COVID-19) comprising administering to a subject (e.g., a human subject) a nucleic acid sequence that comprises a nucleotide sequence encoding at least one, two or more of the following proteins or a combination thereof: MX2, IFIT3, IFITM1, IFI27, IFIT1, BST2, IFI6, RSAD2, IFIH1, MX1, or IFI30. |