| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be554f6d262813fde76c0c034d5eac59 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-335
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3341
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2022-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be18c9ab0ab665b6230cc48384b73f6c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_546913dd24489b2d589b8e25359b7f06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5e3dff7b194f4f4404507cc1db8c96c |
| publicationDate |
2022-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022256354-A1 |
| titleOfInvention |
Short duplex dna as a novel gene silencing technology and use thereof |
| abstract |
The present invention discloses a novel type of gene silencing technology for modulating target nucleic acid and/or protein in cells, tissues, organisms and animals. The new technology provides compositions for use in gene silencing applications, including prevention and treatment of human diseases. The composition comprises a short, duplex DNA molecule where the sense strand is at least equal to the antisense strand in length. The duplex DNA molecule further includes at least one interspersed ribonucleotide monomer. The present invention further provides methods of using the compositions for modulating expression or function of a target gene, or for treatment or prevention of diseases as well as for other medical or biological applications. |
| priorityDate |
2021-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |