| abstract |
A synthetic polymeric porous medium with a core-shell (s) hierarchical layer structure and has an essentially homogeneous porous structure from inside to outside of the medium, whose core and shell (s) are covalently modified with distinct chemical functional groups or same functional group with different density. Here the methodologies for resin syntheses and core-shell (s) modifications and liquid chromatographic applications of the newly developed resins in the field of analysis and purification of Tween surfactants, virus-like particles (VLP) /vaccines/viral vectors/viruses, antibody, and mRNA are disclosed. |