| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5351c62aee4203f2be2944f21a6def2 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M1-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate |
2022-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d5bb8ed4e174f91d8049f51d67d2a98
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d1d2ca5e116e731b2e834d12bc448c5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5be75433371b2efd43e78153bef79ee6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9be2fb9013ed92a78999ae1858c8ddd6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0a0339fb133131d8b69675597e2f946
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78eb8ff2257050d69556a7bdbb2813b8 |
| publicationDate |
2022-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022250406-A1 |
| titleOfInvention |
Non-alcoholic fatty liver artificial tissue model |
| abstract |
The present invention relates to a non-alcoholic fatty liver artificial tissue model. Compared to the prior art in which tissues are cultured only in Matrigel or an extracellular matrix derived from acellular liver tissue, by including a device comprising an extracellular matrix derived from acellular liver tissue and a plurality of microchannels, the present invention can better mimic an actual non-alcoholic fatty liver disease by comprising Kupffer cells and hepatic stellate cells. The present invention has the effect that the growth of liver organoids is not only improved but also fat accumulation and inflammation in the liver organoids are caused to appropriately occur through free fatty acid treatment, and the phenotype of a non-alcoholic fatty liver can be better expressed. |
| priorityDate |
2021-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |