http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022241289-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58c8cf5e272691db3c376434b0aa7f99 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-35 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4705 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
filingDate | 2022-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f98131febabf072f6c340723521c06b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16e4d908bacefbfb12ea7c0d7c306600 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89f455a9dbe1b7d923b81288261b16a2 |
publicationDate | 2022-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2022241289-A2 |
titleOfInvention | Activity-inducible fusion proteins having a transcription factor and a heat shock protein 90 binding domain |
abstract | Activity-inducible fusion proteins including a transcription factor and a heat-shock protein 90 (hsp90) binding domain are described. The activity of the transcription factor is regulated utilizing a drug molecule that binds the hsp90 binding domain. In the absence of the drug molecule, the transcription factor is in an inactive state but can be activated in the presence of the drug molecule. The activity-inducible transcription factors can be used to alter the activation state of immune cells, and optionally can be co-expressed with a chimeric antigen receptor (CAR). |
priorityDate | 2021-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 735.