http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022234639-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59e1d955a7b1560dc68cf7fd800e8fac |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-50 |
| filingDate | 2021-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5474824f64a08f45b4f190b2779edc07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a7047a1b0dfa7b62f40a6db13f46976 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3475373830f7970e4abe0bb0844453b4 |
| publicationDate | 2022-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2022234639-A1 |
| titleOfInvention | Bonding molecule exhibiting selective bonding to variant ras (g12d) |
| abstract | The present inventors discovered that a bonding molecule having the following features (i) and (ii) exhibits significant bonding selectivity to variant RAS (G12D). (i) The bonding molecule directly interacts with Asp12 in variant RAS (G12D), and (ii) the bonding molecule interacts with a Switch2 region in variant RAS (G12D), and with regard to the variant RAS (G12D), intramolecular interaction is exhibited between the Switch2 region and Asp12 in the variant RAS (G12D). Such a molecule may be a promising candidate compound for the treatment and/or prevention of a disease related to the expression of variant RAS (G12D). |
| priorityDate | 2021-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 247.