http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022234194-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_345c329479c46b1f183ee80edc721a1b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2440-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-0203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-60 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 |
| filingDate | 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d80b8ed77ee1e7bdf99c8c0a02118bbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86f8d065f3eb37f9d0904c120834a3a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f6c6692b596c32242f12a02173504ab |
| publicationDate | 2022-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2022234194-A1 |
| titleOfInvention | Method for detecting binding to an adp-ribosyl group or a polymer thereof and a kit for performing said method |
| abstract | The present invention is directed to a method, kit, system and fusion protein for detecting binding to an ADP-ribosyl group or a polymer thereof, wherein said group or polymer is coupled to a peptide or protein, the method comprising the steps of: i) providing a first entity comprising a first label or tag, said entity comprising an amino acid sequence comprising a cysteine residue whereto at least one ADP-ribosyl group or an analog thereof is coupled via an S-glycosidic bond; ii) contacting in an assay said first entity with a second entity, said second entity being or suspected of being capable of binding to an ADP-ribosyl group or polymer thereof coupled to a peptide or protein; and iii) measuring a signal derived from said first label or localized by said tag, wherein the signal detected is different or is localized differently when said second entity binds to said at least one ADP-ribosyl group of the first entity from the signal detected when the binding interaction between said second entity and said ADP-ribosyl group has not occurred. The kit of the present invention provides means to perform the method of the invention. |
| priorityDate | 2021-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 165.