http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022232505-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_852a71e0f8a548a2b2c97a1b6445b1d9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01H5-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01H6-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01H1-101 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82 |
| filingDate | 2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b8cdca285cd99730e5818effc1fe334 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_620d426fe661b7871c1b2f984417182a |
| publicationDate | 2022-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2022232505-A3 |
| titleOfInvention | Toxin-free aloe and methods of making same |
| abstract | Toxin-free mutant aloe has attenuated expression of at least one gene involved in the biosynthesis of a natural toxin, such as aloin. Methods of producing toxin-free mutant aloe involve obtaining plant cells derived from a species of aloe and attenuating the expression level of at least one polyketide synthase gene within the obtained plant cells to form mutant plant cells. Methods further involve culturing the mutant plant cells under a set of culture conditions conducive to proliferation of the mutant plant cells. Methods further involve growing the mutant plant cells in a bioreactor and harvesting a toxin-free aloe bioproduct therefrom. Attenuating the expression level of at least one polyketide synthase gene involves disrupting the gene with a targeted endonuclease system and selecting the successfully mutated cells prior to cell culturing and expansion. |
| priorityDate | 2021-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.