http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022228319-A1

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filingDate 2022-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5075ec7f88a08885808dd2a0e788ad56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_543d3d02f1416e8bba4c4afd5f764a06
publicationDate 2022-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2022228319-A1
titleOfInvention Method for detecting target molecule
abstract A method for detecting a target molecule, comprising mixing a medium particle with a sample containing the target molecule, wherein the medium particle is used to perform two-component surface-enhanced Raman spectroscopy detection on an auxiliary molecule, and the ratio of the spectral number of a single molecule spectrum of the auxiliary molecule to number of spectra that generate a spectral signal is at least 50%; and carrying out surface-enhanced Raman spectroscopy detection on the auxiliary molecule by using the medium particle, the absolute value of a correlation coefficient of signal intensity generated by the auxiliary molecule at any time interval being below 0.3. The method above may achieve liquid-phase digital surface-enhanced Raman spectroscopy detection. The detection method is easy to operate, and the single-molecule level detection sensitivity may be achieved.
priorityDate 2021-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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