Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9fb7bbc09927d64558e1e99a3b7c719b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6907 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70503 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate |
2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1adbe97be9d4ebc71219e1d2db8787f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec713d44ce17bd30221e7f9e7d87005b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17908490a17ccfc0059ee39a2bb1d563 |
publicationDate |
2022-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2022226450-A1 |
titleOfInvention |
Nanocarriers for targeting tumor associated macrophages |
abstract |
Disclosed herein is a nanocarrier system to effectively target TAMs to treat cancer. The disclosed nanocarriers are custom-made extracellular vesicles (EVs) loaded with therapeutic cargo, such as antineoplastic agents, and are functionalized for targeted delivery via decoration with ligands for specific receptors in TAMs. Therefore, also disclosed is a method of inhibiting tumor growth or tumor metastases in a subject in need thereof comprising selectively targeting TAMs. |
priorityDate |
2021-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |