| abstract |
Disclosure herein are an implantable cell containing device, its subcomponent scaffold, methods of making the same and their methods of use. The implantable cell containing device includes a scaffold and a cell -containing hydrogel encapsulating the scaffold. The scaffold has a tracheal-like internal system of continuous air-filled, hydrophobic micro-channels that traverse the scaffold's dimensions and a hydrophilic external surface. The implantable cell containing device, when implanted in a subject, can be used for delivering a therapeutic agent to a subject in need thereof for the treatment of various conditions and diseases. |