Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2ed2441e5a8402b058bac881fc8fd92 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14145 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-075 |
filingDate |
2022-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2f77cbdeeb875568d6b16a13d7ab3db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_799d1a1e5bfa872bbd3cd510e58f685d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b61b7fa82eed0a0a7b416b8c4f84b23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb40460c7b6682baf3cd9ccde5eb0ab4 |
publicationDate |
2022-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2022221420-A2 |
titleOfInvention |
Selected aav compositions having preferred brain enrichment |
abstract |
Described herein are compositions and kits comprising recombinant adeno-associated viruses (rAAVs) with increased viral transduction enrichment in the CNS. The rAAV compositions described herein encapsidate a transgene, such as a therapeutic nucleic acid. Gene therapy using the rAAVs is described. Also described are methods of treating CNS-related diseases and conditions. |
priorityDate |
2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |