| abstract |
The present invention imparts, to a nucleic acid aptamer-type drug, a new property that becomes useful in function as a therapeutic agent or the like. Provided is a covalent drug such as an anti-SARS-CoV-2 drug or the like having such new property. Specifically, provided is an aptamer-type multi-warhead covalent drug having multiple covalent warheads. In particular, provided is an aptamer-type multi-warhead covalent drug targeting SARS-CoV-2. The present invention also provides a pharmaceutical composition containing the multi-warhead nucleic acid aptamer, and a method for producing the multi-warhead nucleic acid aptamer. |