| abstract |
Methods, agents, and pharmaceutical compositions are provided for treating neurodegenerative disease, for enhancing stroke recovery, and or for inhibiting ferroptosis in a subject. These agents, including 2-deoxyglucose, can be used alone or with the right timing in sequential combination with agents that inhibit the integrated stress response. The present invention addresses these needs and provides methods of treating neurodegenerative conditions, including without the need for dietary restrictions which can be challenging in already unwell patients. |