http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022213869-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad4133293dced0f23b8483e126aa1fc4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-554 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-554 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 |
| filingDate | 2022-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_661cae5034361b492e83182bc18c5445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_270f87856f68981f31bca03724d18c52 |
| publicationDate | 2022-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2022213869-A1 |
| titleOfInvention | Method for treating hbv by increasing viral empty capsid protein by means of oral administration |
| abstract | The present invention provides a method for treating HBV by increasing viral empty capsid protein by means of oral administration. Specifically, the present invention provides a compound of formula I, for use in: (a) increasing viral empty capsid; (b) increasing generation of IFN-γ in a liver; (c) reducing the number of CD4+Treg cells in the liver; (d) activating a cGAS/STING/IRF3 signal path in hepatic tissue; and/or (e) reducing the number of virally-infected hepatocytes. The compound of the present invention can convert an immune tolerance environment in the liver into an immunogenicity environment, such that the virally-infected hepatocytes can be effectively removed, and the anti-virus effect is achieved. |
| priorityDate | 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 366.