| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4c6a2eb66d07fad39d708e5a36c9350
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28a89f8dab024e02ae765d1273e716f1 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate |
2022-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50f522107f985498bc2935f31bd6b0eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_83f31e5613ebde1d9e6b887513e28e71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_639d215dd03fc1be2fec45e6769473ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e78500f2aa82c496d108bfc4adced376
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_931868f9df8454569865bb1e75f7c763
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a857a5bb8bad60bc261ecb5f83accdf |
| publicationDate |
2022-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022207846-A1 |
| titleOfInvention |
Therapeutic inhibitors of gdf15 signalling |
| abstract |
This invention relates to antibodies that bind to and inhibit the activity of glial cell-derived neurotrophic factor family receptor alpha like (GFRAL) protein. The invention also relates to the GDF15-GFRAL signalling pathway as a therapeutic target for states of cachexia and conditions involving reduction in food intake and reduction in muscle and fat mass. |
| priorityDate |
2021-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |