http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022204102-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea2d270015848950265808383d7af684 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa91de66e501c516db386ab6af56cf21 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82B3-00 |
filingDate | 2022-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78c028a1ba8e6f98701458cd015ef904 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6867a96da57e077c4eef093640c48381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dac00327c05490233da52ab8aad5615d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d2cfb05f3dfc849e2217a7aab3fa31e2 |
publicationDate | 2022-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2022204102-A1 |
titleOfInvention | Universal linker reagents for dna synthesis |
abstract | Provided herein are methods and compositions for oligonucleotide synthesis utilizing universal linker phosphoramidites. Methods and reagents are described with DNA synthesis using controlled pore glass (CPG) solid supports, and on platinum coated electrodes for electrochemical DNA synthesis. The universal linkers can be used as spacers in single-column PCR primer synthesis to generate 2 strands with free 3'-hydroxy termini after cleavage. The methods and compositions utilize a solid support system for synthesis of oligonucleotides, wherein the support has platinum electrodes and a universal linker, optionally wherein the platinum electrode is coated with an amine. The methods and compositions further describe use of universal linker phosphoramidites and the platinum electrode is coated with a monosaccharide, or a disaccharide. |
priorityDate | 2021-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 283.