Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26ff13972f533eae4d273e1366650d1e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2845 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57434 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
filingDate |
2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da72f2bca69edb079c265eaae07a507f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85a3a7e51f9be8fc61070d3c3549def6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_249b3f838f45f5012e42c8a4c2301e23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24e613f515046fce8fa2c4be956665ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7b190a79bc52a73486a545833b5085d |
publicationDate |
2022-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2022195469-A1 |
titleOfInvention |
Predictive marker for sensitivity to immune checkpoint blockade in prostate cancer and other cancer types |
abstract |
The present invention relates to an in vitro method for identifying and/or selecting those subjects suffering from cancer who are affected by microsatellite instability-like (MSI-like) cancer and/or are responsive immune checkpoint blockade (ICB) therapy, as well as to a kit and computer program enabling the above identification and/or selection. The method involves determining the expression levels of the signature markers CD11b (ITGAM) and/or CD11c (ITGAX). |
priorityDate |
2021-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |