http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022193433-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be2c55a9de09e08e3404c0a5a1ae4dc7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2840-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 |
| filingDate | 2021-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c24fd940fbc9477684638e463498f713 |
| publicationDate | 2022-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2022193433-A1 |
| titleOfInvention | Application of system in improving insertion efficiency of unnatural amino acids |
| abstract | An application of a system in improving insertion efficiency of unnatural amino acids. The system can degrade termination factors (RF1, RF2, ArfB, and Pth) in an Escherichia coli translation system and generates a codon-independent translation termination mechanism. The system can degrade the termination factors in the Escherichia coli translation system and can improve insertion efficiency of simultaneously inserting various unnatural amino acids into a target protein. On a protein level, the termination factors in the Escherichia coli translation system can be completely degraded. After the termination factors in the Escherichia coli translation system are degraded, unnatural amino acids can be inserted into TAG, TGA and TAA codons, thereby realizing insertion of the unnatural amino acids into the three termination codons. |
| priorityDate | 2021-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 138.