http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022192879-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01733884cc888894a4579e6d14f90508 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6911 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-167 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate | 2022-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96f3ad5930d234c743b4819efdf61de6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0821e65979c43e8302eea96805098c6b |
publicationDate | 2022-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2022192879-A1 |
titleOfInvention | Lipid vesicle-mediated delivery to cells |
abstract | The invention concerns a lipid vesicle (LV), such as a liposome, that has been loaded with a cargo molecule covalently or non-covalently coupled to a cell penetrating polypeptide (resulting in a "binding complex"), and the binding complex or cargo molecule has been internalized by, or is associated with, the LV. Another aspect of the invention concerns a method for loading an LV with a cargo molecule, comprising contacting the LV with the binding complex, wherein the binding complex or cargo molecule becomes internalized by, or associated with, the LV. Another aspect of the invention concerns a method for delivering a cargo molecule into a cell in vitro or in vivo, comprising administering a loaded LV to the cell in vitro or in vivo, wherein the loaded LV is internalized into the cell, and wherein the loaded LV comprises the cargo molecule and a cell penetrating polypeptide. |
priorityDate | 2021-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 179.