| abstract |
The present invention provides a polyion complex micelle containing a paramagnetic transition metal element, a super-paramagnetic transition metal element or a ferromagnetic transition metal element. The present invention provides a polyion complex micelle which includes therein a paramagnetic transition metal element, a super-paramagnetic transition metal element or a ferromagnetic transition metal element and a chelating agent (e.g., 1,4,7,10-tatraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA)), the polyion complex micelle comprising (A) a cationic polymer and (B) an anionic polymer, in which at least one of the components (A) and (B) is a block copolymer with a non-charged hydrophilic polymer, and the chelating agent may be linked to the polycationic polymer block or the polyanionic polymer block. |