| abstract |
Provided is a photosensitizer which has a specific structure, and has higher sensitivity than existing photosensitizers when light irradiation causes a rapid change from hydrophilicity to hydrophobicity. The present invention pertains to: a photosensitizer containing a metal complex which is represented by general formula (1) or general formula (2) and has a cyclic ligand that forms a ring structure in which pyrrole rings are linked directly or via π conjugation, and an axial ligand having an onium salt structure; an antibody conjugate to which said photosensitizer binds; a method of using said photosensitizer, the method being characterized in that the detachment of an axial ligand is promoted through irradiation with light having a wavelength of 500-1,500 nm; and a usage method in which said photosensitizer is used for therapeutic purpose. |