| abstract |
A bioreactor with a closed vessel, a reaction chamber, and at least one barrier, wherein the bioreactor is configured to support a biologically active environment. The barrier for the reaction chamber of the bioreactor includes pores and a media flow path connected to the pores. The media flow path is configured to have a diameter that is smaller than the average diameter of the pores. The barrier of the bioreactor includes a surface feature, internal structural feature, or combinations thereof, which are configured to improve or enhance the growth of cells or microorganisms. |