Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7296bd79043366c6560505c24c09d281 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-04 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07049 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0664 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 |
filingDate |
2021-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a790c52d68d00e9b0ec187a8d8925ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_278bcb2c5b9057e897e271e5ae750490 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7d7a04532b92a0d246d4de03a73e0d8 |
publicationDate |
2022-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2022144333-A1 |
titleOfInvention |
Extracellular vesicles derived from mesenchymal stromal cells genetically modified to overexpress hif-1a and htert |
abstract |
The present invention refers to extracellular vesicles (EVs) isolated from mesenchymal stromal cells genetically modified to overexpress HIF-1α and hTERT (MSCs-T- HIF). The present invention also refers to the method for obtaining the extracellular vesicles. Finally, the clinical applications of the EVs in cellular therapy, in particular for the treatment of autoimmune diseases and ischemic diseases are also contemplated. |
priorityDate |
2020-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |