| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1761 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 |
| filingDate |
2021-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e3bff4325fdd1c78488c05e7b0d5aa9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e690f3c37ed75e286e9a7bee785c1b8 |
| publicationDate |
2022-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022140118-A1 |
| titleOfInvention |
Compositions and methods for treating patients with mitochondrial complex i deficiency using caspase-9 signaling pathway inhibitors |
| abstract |
The present disclosure relates to a method for treating mitochondrial complex I deficiency comprising administering to patients with mitochondrial complex I deficiency an effective amount of XBIR3. The effective amount of XBIR 3 may be conjugated to a cell-penetrating peptide, such conjugation may include encapsulation of XBIR3 in nano-carrier that is conjugated to a cell penetrating peptide or direct conjugation of XBIR3 to a cell penetrating peptide. The XBIR-3 conjugated to a cell-penetrating peptide may be administered directly to the eye of the patient, administered systemically, or administered intranasally. |
| priorityDate |
2020-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |