| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47ddf9350e933f26adf5fbcf4f95fc9a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-4145 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3278
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6825 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6834
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
| filingDate |
2021-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba1ad5ce6e7624014c0f5bf09a6c91f7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35b881fb99ec2ca515a638ebb23500fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f65aa2b9c1b8a4123a0d1d62a046770
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eeb3ef45a67b717f0f88002c107fc482
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dac196aeac0118e6e322c4d6cab4b45d |
| publicationDate |
2022-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022139886-A1 |
| titleOfInvention |
Crispr enzyme circuits for molecular electronic sensors |
| abstract |
In various embodiments of the present disclosure, a molecular electronics sensor comprising a CRISPR Cas enzyme/crRNA complex is described. The CRISPR Cas enzyme/crRNA molecular electronics sensor may be one of a plurality of such sensors configured in a sensor array on a CMOS chip. The sensor array chip is capable of detecting nucleic acid targets hybridizing with the crRNA and/or complexing with the CRISPR Cas enzyme in the individual sensor pixels, wherein molecular interactions and/or Cas enzyme activity are seen as perturbations in a measured electrical parameter of the sensor circuits, such as signals or a signature of signals in a current versus time trace. |
| priorityDate |
2020-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |