| abstract |
The present invention provides a spherical culture for which quantitative analysis can be easily performed for a region including brain neurons, which is useful as a supply source of neurons for transplantation, and which can be suitably used in an evaluation system for a compound or drug discovery screening for a neurological disorder.　Provided are: a spherical culture comprising a first cell layer that includes neural stem cells and/or neuronal precursor cells, and a second cell layer that includes brain neurons, wherein the first cell layer exists on a surface part of the spherical culture; and a manufacturing method for the spherical culture. |