| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f8fe90bd741939b669967410a817918 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6851
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6849
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6889
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2021-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cbe276f466fa5eecf69e3469af0a73a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89e2340f0d11b41f8edba91c9429bc33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ed9ac967d4802e4ade2ed9ae467c70e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cf036e3fec8e73880f0f905956be0c5 |
| publicationDate |
2022-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022136705-A1 |
| titleOfInvention |
Glycan-conjugated antibodies binding to fc-gamma receptor |
| abstract |
The present invention provides antibody-conjugates which are conjugated via the glycan and still bind to a cell comprising an Fc-gamma receptor. The antibody conjugates according to the invention have structure (1): Ab–[(GlcNAc(Fuc)b–(G)e–(Su–(Z–L–(D)r)x)s]y (1). Herein, Ab is an antibody; GIcNAc is an N-acetylglucosamine moiety; Fuc is a fucose moiety; b is 0 or 1; G is a monosaccharide; e is an integer in the range of 4 - 10; Su is a monosaccharide; Z is a connecting group obtained by a cycloaddition or a nucleophilic reaction; L is a linker; D is a payload; s is 1 or 2; r is an integer in the range of 1 - 4; x is 1 or 2; y is 2 or 4. |
| priorityDate |
2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |