http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022136452-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42dace48f4efac5b7912d0b6a78a14ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df9e267f2bcc2804684e73febfbc6711 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 |
| filingDate | 2021-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa5c4044bcc1be0de69e4224df753e25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea69424094e54da180817e0baed3c052 |
| publicationDate | 2022-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2022136452-A1 |
| titleOfInvention | A platform to obtain monoclonal antibodies directed against processed tumor-specific antigens |
| abstract | It forms an object of the present invention a method to obtain monoclonal antibodies, or fragments or conjugates thereof, which bind with high affinity to a target protein which is a protein specifically expressed in local and metastatic tumors, preferably said target protein being Trop-2, wherein said method comprises: - making available an immunogenic material, wherein the immunogenic material is selected in the group comprising the target protein, fragments and conjugates thereof produced in different organisms, including tumor cells that naturally express the processed target protein and mammalian transformed and tumor cells, insect cells, yeast cells, bacterial cells that have been transfected with vectors that express the target protein and fragments thereof, also as fusion proteins with other sequences; - administering to a non-human animal one of said immunogenic material. |
| priorityDate | 2020-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 463.