| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3fa9d3e06cf00a61c051432f0e1c3c4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate |
2020-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab689c852b41bc9b8117c4f28e70ca5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0e60ca4a7cd51e41881d52c3b0dd549
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd2b4b0668f2b1d8fc1dddf467bd861e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a01117ef61c56c3b060edcb290fd4bd8 |
| publicationDate |
2022-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022131408-A1 |
| titleOfInvention |
Method for preparing high-purity antisense oligonucleotide |
| abstract |
The present invention relates to a method for preparing a high-purity antisense oligonucleotide. The antisense oligonucleotide intended to be synthesized by the present inventors is a nucleic acid therapeutic agent having a PS backbone as an 18-mer single DNA sequence, wherein a synthesizer AKTA OligoPilot 100 (OP100) is used in the development of a synthesis process, and the antisense oligonucleotide preparation method increases yield and purity by optimizing parameters for each step. The present invention enables the preparation of an antisense oligonucleotide having minimized impurities. |
| priorityDate |
2020-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |