| abstract |
Lactobacillus reuteri CCFM1132 for alleviating hyperuricemia and ulcerative colitis, and an application, relating to the technical field of microorganisms. The Lactobacillus reuteri CCFM1132 is capable of lowering the serum uric acid level of a hyperuricemia mouse, inhibiting the activity of xanthine oxidase (XOD) in serum and liver, and reducing the occurrence of hyperuricemia and gout, is capable of down-regulating the serum creatinine level, down-regulating the overall triglyceride (TG) level in serum, and inhibiting the activity of alkaline phosphatase (ALP) in serum, and is capable of promoting expression of an intestinal uric acid transporter ABCG2. The Lactobacillus reuteri CCFM1132 is capable of improving a disease activity index for a patient suffering from colitis, can be used for preparing functional bacteriological agents, foods, and drugs for alleviating hyperuricemia, gout, and inflammatory bowel diseases, and has a wide application prospect. |