| abstract |
The present invention relates to a nucleic acid molecule for induction of asymmetric RNAi for inhibiting expression of RAR related orphan receptor B (ROR-beta) and a use thereof and, more specifically, to a nucleic acid molecule for induction of asymmetric RNAi, the molecule comprising an antisense strand including a complementary sequence to an mRNA coding for ROR-beta, and a sense strand forming a complementary bond with the antisense strand, and a pharmaceutical composition for alleviation or treatment of a retinal disease, the composition comprising the nucleic acid molecule for induction of asymmetric RNAi. |