| abstract |
Disclosed herein are methods for treating inflammatory disorders of the joints, optionally rheumatoid arthritis, or at least one symptom thereof, comprising administering to a subject in need thereof an effective amount of: an immunosuppressant; and one or more Lactobacillus species selected from Lactobacillus buchneri, Lactobacillus paracasei, Lactobacillus zeae, Lactobacillus rapi, Lactobacillus parafarraginis, and Lactobacillus diolivorans, and/or a culture supernatant or cell free filtrate derived from culture media in which said one or more Lactobacillus species has been cultured. In particular embodiments, the method comprises the administration of a combination of an immunosuppressant, Lactobacillus buchneri, Lactobacillus paracasei and Lactobacillus zeae. |