Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_acb2bffaf3f30d2b0acb0ac1d2f6d7d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3c59a75d8ffaf05c8e9883f0c8c9f9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1131 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-465 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
filingDate |
2021-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f90b722819e2f0321508950e8417d1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc0b5fa4938ebf96d7a6691d51d985a1 |
publicationDate |
2022-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2022119919-A1 |
titleOfInvention |
Compositions and methods for cleaving viral genomes |
abstract |
Disclosed are methods of inactivating a vims in a cell comprising administering to a cell comprising a viral genome, a Cas12d or Cas12e endonuclease, or a nucleic acid constuct that encodes the Cas12d or Cas12e endonuclease; and a first guide RNA (gRNA), or a nucleic acid constuct that encodes the first gRNA, wherein the Cas12d or Cas12e endonuclease cleaves the viral genome at a first target sequence and a second target sequence in the viral genome. |
priorityDate |
2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |