| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_431309bc8dab94a0ee0e2aa5aeacd48d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5438
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54306
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 |
| filingDate |
2021-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_257be230f750068c93c51e51e33ae7e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fd0898ed9c9ca6c5f5d5a19b3fb3d16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4352207263b8b5451f9f4f1f0652c03f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38d3733a7aa70a544e7b2341d7d646ee |
| publicationDate |
2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022109247-A1 |
| titleOfInvention |
Viral vector potency assay |
| abstract |
The present disclosure provides sensitive and robust assays for determining the potency of recombinant viral vectors. Particularly, the present disclosure provides assays to determine the potency of AAV2 recombinant viral vectors expressing REP1 for the treatment of choroideremia. The methods involve a prenylation assay and are used to determine the biological activity of a protein such as REP-1 or to determine the quantity of the expressed protein. |
| priorityDate |
2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |