| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_282d8844066f5f683bc2463742373508 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-104
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
| filingDate |
2020-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7646c240e44e88309463485c8bab23b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94fa600f13faabc9ea1c592d3b931425
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8035f2aa7267a2bc4852ed6617a859be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49b56d08cdf2cf9c5c433ba32982850e |
| publicationDate |
2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2022106869-A1 |
| titleOfInvention |
Fusion proteins comprising an e2 ubiquitin or ubiquitin-like conjugating domain and a targeting domain for specific protein degradation |
| abstract |
The disclosure provides a molecule comprising a regulation domain comprising an E2 ubiquitin or ubiquitin-like conjugating domain which has an amino acid sequence having at least 80% sequence identity to a human E2 ubiquitin or ubiquitin-like domain, and a targeting domain capable of targeting the regulation domain to a substrate. Also provided are polynucleotides encoding such molecules, methods of identifying and producing the same, and related pharmaceutical compositions and kits suitable for use, among other things, in treating or preventing a disease and/or condition in a subject that is mediated by a dysregulated substrate. |
| priorityDate |
2019-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |